Relationship between coping ways with stress and IL-6 Immunologic biomarker in Coronary Heart Disease Patients

Introduction: Coping ways with stress in coronary heart disease can lead to significant changes in levels of IL-6 Immunologic Biomarker. The aim of this study was to examine the relationship between coping ways with stress and IL-6 immunologic biomarker in coronary heart disease patients. Methods: In this experimental study, the subjects were 44 patients with confirmed CHD, admitted to the private sector hospitals. At least one major coronary vessels with more than 90% stenosis confirmed by angiography was inclusion crileria coping ways questionnaire- Lazarus and Folkman and human IL-6 kit (Bender Med System Manufacturing Co, Austria) with ELISA method measure were used. Statistical methods included mean, standard deviation, Pearson correlation and multiple regression analysis. Results: The results showed that there and significant positive correlation between emotional focused coping ways and immunologic IL-6 biomarker significant negative correlation between problem focused coping ways and Immunologic IL-6 biomarker, and 63% of total variance IL-6 biomarker are representation by coping ways. Coefficient of Emotional focused coping ways according to T-test showed that these variables with 0.99 reliably can anticipate changes related to IL-6 biomarker. Continuous regression coefficient showed that problem focused coping ways can significantly explain variance of IL-6 biomarker in coronary heart disease patients. Conclusion: We concluded that using emotional focused coping ways may lead to an a increases levels of IL-6. Using of problem focused coping ways may lead to decreased in levels of IL-6.